Title:
10,10’-置換-9,9’-ビアクリジン発光分子誘導体及びシグナル溶液の調製
Document Type and Number:
Japanese Patent JP3989537
Kind Code:
B2
Abstract:
The synthesis of 10,10'-substituted-9,9'-biacridine molecules and their derivatives is disclosed. These molecules are shown to catalyze the production of light by chemiluminescence in the presence of a signal solution having at a pH from about 10.0 to about 14.0, at a concentration effective for producing a chemiluminescent signal, a chelating agent, a sulfoxide, a reducing sugar, an oxidant or combination of oxidants, an alcohol and aqueous sodium tetraborate. These 10,10'-substituted-9,9'-biacridines are used alone or attached to haptens or macromolecules and are utilized as labels in the preparation of chemiluminescent, homogeneous or heterogeneous assays. They are also used in conjunction with other chemiluminescent label molecules to produce multiple analyte chemiluminescent assays.
Inventors:
Katshiro Methes George W
Application Number:
JP50334096A
Publication Date:
October 10, 2007
Filing Date:
June 22, 1995
Export Citation:
Assignee:
Katshiro Methes George W
International Classes:
C07D219/02; G01N33/53; C07D401/14; C07K14/00; C07K16/00; C07K16/26; C12P21/08; G01N33/532; G01N33/533; G01N33/543; G01N33/58
Domestic Patent References:
| JP4507194A | ||||
| JP4506403A |
Foreign References:
| US4478817 |
Other References:
Analytica Chimica Acta, 1994年, Vol.290, pp.179-185
J. Photochem. Photobiol. A: Chem., 1993年, Vol.75, pp.91-96
Bull. Chem. Soc. Jpn., 1993年, Vol.66, pp.2659-2664
Bull. Chem. Soc. Jpn., 1993年, Vol.66, pp.1834-1836
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Tetrahedron Letters, 1993年, Vol.34, No.8, pp.1371-1372
Journal of Bioluminescence and Chemiluminescenece, 1989年, Vol.4,pp.164-176
J. Photochem. Photobiol. A: Chem., 1993年, Vol.75, pp.91-96
Bull. Chem. Soc. Jpn., 1993年, Vol.66, pp.2659-2664
Bull. Chem. Soc. Jpn., 1993年, Vol.66, pp.1834-1836
J. prakt. Chem., 1993年, Vol.335, pp.633-636
Tetrahedron Letters, 1993年, Vol.34, No.8, pp.1371-1372
Journal of Bioluminescence and Chemiluminescenece, 1989年, Vol.4,pp.164-176
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Shishido Kaichi
Nobuo Ogawa
Kenji Asai
Fumiaki Otsuka
Shishido Kaichi
Nobuo Ogawa
Kenji Asai