Title:
HIV特異的細胞傷害性T細胞応答
Document Type and Number:
Japanese Patent JP3996349
Kind Code:
B2
Abstract:
A method of generating an HIV-specific cytotoxic T-cell response in a host involves an initial administration of a T-helper molecule to the host to prime T-helper cells of the immune system of the host and a subsequent administration to the host of a mixture of the T-helper molecule and a T-cell inducing HIV-derived molecule to generate an HIV-specific T-cell response in the host.
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Inventors:
Shire, Charles Dee.
Chang, Pele
Crane, Michael H.
Chang, Pele
Crane, Michael H.
Application Number:
JP2000542037A
Publication Date:
October 24, 2007
Filing Date:
April 01, 1999
Export Citation:
Assignee:
SANOFI PASTEUR LIMITED
International Classes:
A61K39/21; C12Q1/02; A61K39/29; A61K39/39; A61P31/18; A61P37/04; A61P43/00; C07K14/02; C07K14/16; A61K39/00
Domestic Patent References:
| JP7502729A | ||||
| JP2001504812A | ||||
| JP6510051A |
Foreign References:
| FR2713651A1 |
Other References:
VAN,B.A. et al,Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inverse, J Gen Virol,1997年,Vol.78 , No. Pt 8,,p.1913-8
Blazevic V et al.,AIDS Res Hum Retroviruses.,1995年11月,11(11),1335-42
Deprez B et al.,Vaccine. ,1996年 4月,14(5),375-82
Blazevic V et al.,AIDS Res Hum Retroviruses.,1995年11月,11(11),1335-42
Deprez B et al.,Vaccine. ,1996年 4月,14(5),375-82
Attorney, Agent or Firm:
Akio Miyazaki
Nobuyuki Kaneda
Katsuhiro Ito
Ishibashi Masayuki
Nobuyuki Kaneda
Katsuhiro Ito
Ishibashi Masayuki