Title:
生物活性物質放出コーティングと制御された湿潤法
Document Type and Number:
Japanese Patent JP4008921
Kind Code:
B2
Abstract:
A coating composition in the form of a one or multi-part system, and method of applying such a composition under conditions of controlled humidity, for use in coating device surfaces to control and/or improve their ability to release bioactive agents in aqueous systems. The coating composition is particularly adapted for use with medical devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such as stents and catheters. The composition includes the bioactive agent in combination with a first polymer component such as polyalkyl(meth)acrylate, polyaryl(meth)acrylate, polyaralkyl(meth)acrylate, or polyaryloxyalkyl(meth)acrylate and a second polymer component such as poly(ethylene-co-vinyl acetate).
Inventors:
Chappa, Ralfue.
Hagen Rosser, Robert W.
Anderson, Aaron Bee.
Trang, Limbuy.
Rawin, Raleigh Earl.
Offstead, Ronald F.
Hagen Rosser, Robert W.
Anderson, Aaron Bee.
Trang, Limbuy.
Rawin, Raleigh Earl.
Offstead, Ronald F.
Application Number:
JP2004512819A
Publication Date:
November 14, 2007
Filing Date:
June 18, 2003
Export Citation:
Assignee:
Thermo Dicks, Incorporated
International Classes:
A61L29/00; A61L31/00; A61F2/82; A61K31/565; A61L17/00; A61L27/00; A61L29/08; A61L29/16; A61L31/10; A61L31/16; A61K47/32
Domestic Patent References:
| JP7165609A | ||||
| JP9194347A | ||||
| JP7145056A | ||||
| JP2002512856A | ||||
| JP7017851A | ||||
| JP7053835A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuo Yoshii
Takashi Ishida
Tetsuji Koga
Kazuo Yoshii
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