Title:
縮合ベンズアミド化合物及びバニロイド受容体1型(VR1)活性阻害剤
Document Type and Number:
Japanese Patent JP4018739
Kind Code:
B2
Abstract:
To provide a compound having an excellent inhibitory effect on vanilloid receptor subtype 1 (VR1) activity which is effective in treating diseases to which the vanilloid receptor subtype 1 (VR1) activity is involved, such as pain, acute pain, chronic pain, neuropathic pain, rheumatoid arthritis pain, neuralgia, etc. and a pharmaceutical composition containing the compound. The object has been attained by a condensed benzamide compound represented by the following formula (the symbols in the formula have the same meanings defined in the specification) or its salt:
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Inventors:
Yoshihisa Koga
Shinji Yada
Takashi Watanabe
Takuya Matsuo
Takayuki Yamazaki
Masahiro Sakata
Wataru Kondo
Hidekazu Ozeki
Yoshikazu Hori
Shinji Yada
Takashi Watanabe
Takuya Matsuo
Takayuki Yamazaki
Masahiro Sakata
Wataru Kondo
Hidekazu Ozeki
Yoshikazu Hori
Application Number:
JP2006529289A
Publication Date:
December 05, 2007
Filing Date:
July 14, 2005
Export Citation:
Assignee:
Japan Tobacco Inc.
International Classes:
C07D413/04; A61K31/498; A61K31/538; A61K31/553; A61P1/00; A61P1/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/10; A61P17/04; A61P25/00; A61P25/04; A61P25/28; A61P29/00; C07D265/36; C07D401/04; C07D413/14; C07D417/14
Foreign References:
WO2006006740A1 | ||||
WO2003097586A1 | ||||
WO2003068749A1 | ||||
WO2003080578A1 | ||||
WO2003099284A1 | ||||
WO2003053945A1 |
Other References:
Tetrahedron Letters,43,pp.3903-3906,(2002)
Attorney, Agent or Firm:
Teruo Daito