Title:
神経膠細胞系由来神経栄養因子(GDNF)タンパク質産物を使用する感覚神経性聴力損失及び前庭障害の予防及び治療方法
Document Type and Number:
Japanese Patent JP4028598
Kind Code:
B2
Abstract:
The present invention relates generally to methods for preventing and/or treating injury or degeneration of cochlear (and vestibular) hair cells and spiral ganglion neurons (as well as vestibular neurons-Carpa's neurons) by administering glial cell line-derived neurotrophic factor (GDNF). The invention relates more specifically to methods for treating sensorineural hearing loss and vestibular disorders.
Inventors:
Ella Maygal
Application Number:
JP53032397A
Publication Date:
December 26, 2007
Filing Date:
February 14, 1997
Export Citation:
Assignee:
Amjien Incorporated
International Classes:
A61K38/22; A61K38/18; C12N15/09; A61K48/00; A61P25/02; A61P27/16; C07K14/48; C12N15/12; C12P21/02
Domestic Patent References:
| JP7502980A |
Other References:
ZHENG, J. L. et al, J Neurobiol, 1995年, Vol.28, No.3, pp330-340
Attorney, Agent or Firm:
Yoshio Kawaguchi
Takeshi Funayama
Naoya Fushimi
Takeshi Funayama
Naoya Fushimi