Title:
消化器系疾患の予防、治療用組成物
Document Type and Number:
Japanese Patent JP4065642
Kind Code:
B2
Abstract:
The present invention provides a composition for safely and effectively preventing and treating digestive organs diseases, particularly, gastric ulcer, duodenal ulcer, gastritis, diarrhea, enteritis and the like. There is also provided a composition having a novel mechanism of action in order to solve the problems which was difficult to be solved by the side effect previously known mechanisms of action. More particularly, there is provided a pharmaceutical composition containing an ingredient which activates PAR-2 as an essential ingredient, which is useful for inhibiting gastric acid secretion, promoting digestive tract mucus secretion, protecting digestive tract mucosa, repairing tissue of digestive organs, and preventing and treating digestive organs diseases.
Inventors:
Hiromasa Araki
Atsushi Kawabata
Ryotaro Kuroda
Kakehi Kazuaki
Shuichi Tanaka
Kenzo Kawai
Nishimura Koyo
Hiroyuki Nishikawa
Atsushi Kawabata
Ryotaro Kuroda
Kakehi Kazuaki
Shuichi Tanaka
Kenzo Kawai
Nishimura Koyo
Hiroyuki Nishikawa
Application Number:
JP2000047515A
Publication Date:
March 26, 2008
Filing Date:
February 24, 2000
Export Citation:
Assignee:
FUSO PHARMACEUTICAL INDUSTRIES,LTD.
International Classes:
A61K9/00; A61K38/00; A61K38/08; A61K38/17; A61K38/46; A61K38/55; A61K45/00; A61K45/06; A61P1/04; A61P1/12
Domestic Patent References:
| JP9301866A | ||||
| JP9136832A |
Foreign References:
| WO1998003182A1 |
Other References:
McConalogue K. et al.,Gastroenterology,1997年,Vol.112,No.4,p.A1171
白井孝之,Medicina,1994年,Vol.31,NO.1,p.30-34
川畑篤史等,プロテアーゼ受容体(PAR)の生理的役割:特に消化器系機能への関与について,日本薬理学雑誌,1999年,Vol.114,捕冊1,p.173P~179P
白井孝之,Medicina,1994年,Vol.31,NO.1,p.30-34
川畑篤史等,プロテアーゼ受容体(PAR)の生理的役割:特に消化器系機能への関与について,日本薬理学雑誌,1999年,Vol.114,捕冊1,p.173P~179P
Attorney, Agent or Firm:
Aoyama Aoi
Mitsuo Tanaka
Mitsuo Tanaka