Title:
組換えアデノウイルスワクチン
Document Type and Number:
Japanese Patent JP4093597
Kind Code:
B2
Abstract:
The production of antibodies or cell mediated immunity to an infectious organism in a warm blooded mammal is disclosed. The production comprises administering to the said warm blooded mammal intranasally, intramuscularly, or subcutaneously, live recombinant adenoviruses in which the virion structural protein is unchanged from that in the native adenovirus from which the recombinant adenovirus is produced, and which contain the gene coding for the antigen corresponding to said antibodies or inducing said cell mediated immunity. Vaccines containing the live recombinant adenoviruses are also described. Some of the recombinant adenoviruses are new per se.
Inventors:
Alan Robert Davis
Paul Powen Hung
Michael david lubeck
Robert James Natuck
Pranab Kumar Chanda
Shridara Chicatur Shankaranarayana Mercy
Shaw-Guang Lin Lee
Paul Powen Hung
Michael david lubeck
Robert James Natuck
Pranab Kumar Chanda
Shridara Chicatur Shankaranarayana Mercy
Shaw-Guang Lin Lee
Application Number:
JP19341093A
Publication Date:
June 04, 2008
Filing Date:
August 04, 1993
Export Citation:
Assignee:
Wyeth
International Classes:
A61K39/235; A61K39/295; A61K39/21; A61P31/12; A61P31/18; C07K14/16; C12N7/00; C12N7/01; C12N15/09; C12N15/861; C12P21/00; A61K39/00; C12R1/92
Foreign References:
| WO1992011028A1 |
Other References:
Journal of Virology(1989)Vol.63,No.1,p.129-136
Virology(1990)Vol.175,No.2,p.535-547
Journal of General Virology(1991)Vol.72,No.6,p.1243-1251
Natural Immunity and Cell Growth Regulation(1990)Vol.9,No.3,p.160-164
Virology(1990)Vol.175,No.2,p.535-547
Journal of General Virology(1991)Vol.72,No.6,p.1243-1251
Natural Immunity and Cell Growth Regulation(1990)Vol.9,No.3,p.160-164
Attorney, Agent or Firm:
Aoyama Aoi
Mitsuo Tanaka
Mitsuo Tanaka