Title:
冠動脈形成術後再狭窄のリスク診断方法
Document Type and Number:
Japanese Patent JP4129908
Kind Code:
B2
Abstract:
It is intended to provide a means of diagnosing genetic risk of restenosis after coronary angioplasty which shows a high accuracy and a high estimation ratio. The risk of restenosis after coronary angioplasty is diagnosed by a method comprising the following steps: (i) the step of analyzing 2 or more polymorphisms among 6 gene polymorphisms proved as relating to restenosis after balloon expansion or 5 gene polymorphisms proved as relating to restenosis after stent insertion; (ii) the step of determining the genotype of a nucleic acid sample based on the polymorphism data obtained in the above step; and (iii) the step of determining the genetic risk of restenosis after coronary angioplasty form the genotype thus determined.
Inventors:
Yoshida Yamada
Mitsuhiro Yokota
Mitsuhiro Yokota
Application Number:
JP2002233041A
Publication Date:
August 06, 2008
Filing Date:
August 09, 2002
Export Citation:
Assignee:
Nagoya Institute of Industrial Science
Gifu Research and Development Foundation
Gifu Research and Development Foundation
International Classes:
C12N15/09; C12M1/00; C12Q1/68; G01N33/53; G01N33/566
Other References:
The Pharmacogenomics Journal,2002年 6月,Vol.2,pp.197-201
Thromb. Haemost.,2000年,Vol.83,pp.392-396
Atherosclerosis,1994年,Vol.110,pp.195-202
Blood,1999年,Vol.93, No.8,pp.2449-2453
Molecular Medicine,2001年,第38巻 臨時増刊号,pp.242-246
Human Genet.,2002年 1月,Vol.110, No.1,pp.89-94
Thrombosis Research,2001年,Vol.104,pp.181-186
Thromb. Haemost.,2000年,Vol.83,pp.392-396
Atherosclerosis,1994年,Vol.110,pp.195-202
Blood,1999年,Vol.93, No.8,pp.2449-2453
Molecular Medicine,2001年,第38巻 臨時増刊号,pp.242-246
Human Genet.,2002年 1月,Vol.110, No.1,pp.89-94
Thrombosis Research,2001年,Vol.104,pp.181-186
Attorney, Agent or Firm:
Tomimasa Konishi
Tomoko Nakamura
Mikiharu Hagino
Tomoko Nakamura
Mikiharu Hagino