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Title:
疎水性ポリペプチドの細菌生産
Document Type and Number:
Japanese Patent JP4131554
Kind Code:
B2
Abstract:
Methods for the production of interferon- beta polypeptides by bacterial cells, by culturing cells capable of producing IFN- beta polypeptide under conditions that induce increased production of IFN- beta polypeptide. Such conditions include, for example, low potassium cation concentration and/or very low sodium cation concentration and/or specific pH ranges.

Inventors:
Glenn, Drin
McAllary, Patrick Jay.
One, Catherine M.
Application Number:
JP50154497A
Publication Date:
August 13, 2008
Filing Date:
June 05, 1996
Export Citation:
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Assignee:
Chiron Corporation
International Classes:
C12N15/09; A61K38/21; C07K14/565; C12N1/21; C12N15/22; C12P21/02; C12R1/19
Domestic Patent References:
JP59093093A
JP62282586A
JP6269292A
JP2227075A
JP62278982A
Foreign References:
US4499188
Attorney, Agent or Firm:
Hidesaku Yamamoto