Title:
分子コーミングによる遺伝病の診断法および診断用キット
Document Type and Number:
Japanese Patent JP4226078
Kind Code:
B2
Abstract:
The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterised in that it consists in: (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridised probes) for determining therefrom the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.
Inventors:
Aaron, Ben Simon
David, Ben Simon
Xavier, Michelle
David, Ben Simon
Xavier, Michelle
Application Number:
JP52013998A
Publication Date:
February 18, 2009
Filing Date:
October 30, 1997
Export Citation:
Assignee:
Institute, Pasteur
Centre National De La Recherche Scientifique (C.N.R.S)
Centre National De La Recherche Scientifique (C.N.R.S)
International Classes:
C12N15/09; C12Q1/68; G16B20/10
Domestic Patent References:
| JP7506259A |
Foreign References:
| WO1995021939A1 |
Other References:
Cellular and Molecular Biology. 1995, Vol.41, No.7, p.925-931
Cytometry. 1994, Vol.15, No.3, p.193-198
Cytometry. 1994, Vol.15, No.3, p.193-198
Attorney, Agent or Firm:
Kazuo Sato
Onodera Kyohiro
Yukitaka Nakamura
Noritaka Yokota
Onodera Kyohiro
Yukitaka Nakamura
Noritaka Yokota
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