Title:
蛋白質の立体構造の推定方法
Document Type and Number:
Japanese Patent JP4243423
Kind Code:
B2
Abstract:
A method of predicting a scaffold of a protein comprising a query sequence, wherein said method uses a database which contains environmental information on the side chain of each amino acid residue contained in the amino acid sequence of each reference protein whose three-dimensional structure is known or predictable, and wherein said method comprises the step of: conducting matching based on the environmental information on each amino acid residue of each reference protein and hydrophobicity or hydrophilicity property of the side chain of each amino acid residue of the query sequence, and choosing at least one template protein among the reference proteins that has high similarity in three-dimensional structure to the protein comprising the query sequence.
Inventors:
Akiko Itai
Application Number:
JP2000515182A
Publication Date:
March 25, 2009
Filing Date:
October 02, 1998
Export Citation:
Assignee:
Akiko Itai
Pharmaceutical Molecular Design Laboratory Co., Ltd.
Pharmaceutical Molecular Design Laboratory Co., Ltd.
International Classes:
G01N33/68; C07K1/00; C07K14/00; G06F15/18; G06F17/00; G16B15/20
Domestic Patent References:
| JP7206894A | ||||
| JP6110944A | ||||
| JP10287696A |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes