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Title:
ホスホリルコリン基含有多糖類及びその製造方法
Document Type and Number:
Japanese Patent JP4248189
Kind Code:
B2
Abstract:
The present invention is a method for manufacturing a phosphorylcholine group-containing polysaccharide wherein the aldehyde derivative-containing compound obtained by the oxidative ring-opening reaction of glycerophosphorylcholine is added to a polysaccharide containing amino groups as well as a new polysaccharide having phosphorylcholine groups obtained from this manufacturing method. The object of the present invention is to provide a phosphorylcholine group-containing polysaccharide that is superior in biocompatibility and moisture retention, and is useful as a polymer material for medical use, as well as a simple method of manufacturing it. The polysaccharide of the present invention is utilized, for example, in artificial organs, biomembranes, coating agents for medical tools, drug delivery, and in cosmetics.

Inventors:
Kazufumi Miyazawa
Toshio Ryoki
Winnick Francois
Application Number:
JP2002106356A
Publication Date:
April 02, 2009
Filing Date:
April 09, 2002
Export Citation:
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Assignee:
SHISEIDO COMPANY,LTD.
International Classes:
A61L27/00; C08B15/06; A61K8/60; A61K8/73; A61K47/36; A61Q19/00; C08B11/20; C08B15/00; C08B37/00; C08B37/02; C08B37/08
Domestic Patent References:
JP62258390A
JP61500918A
JP10087702A
Attorney, Agent or Firm:
▲高▼野 俊彦