Title:
ピラノンプロテアーゼインヒビターの経口投与自己乳化製剤
Document Type and Number:
Japanese Patent JP4298998
Kind Code:
B2
Abstract:
A microemulsion of pyranone protease inhibitor compounds that is substantially free of alcohol and propylene glycol comprising a pyranone protease inhibitor, one or more pharmaceutically acceptable surfactants, and a polyethylene glycol solvent having a mean molecular weight of greater than 300 but lower than 600, and a lipophilic component comprising medium chain mono- and di-glycerides, and optionally a basic amine.
Inventors:
Chen Charlin
Gun Joslin A
Gun Joslin A
Application Number:
JP2002538922A
Publication Date:
July 22, 2009
Filing Date:
October 30, 2001
Export Citation:
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
International Classes:
A61K31/4433; A61K9/107; A61K9/48; A61K31/352; A61K31/366; A61K31/37; A61K47/14; A61K47/18; A61K47/34; A61P31/18; A61P35/02; A61P37/04; A61P43/00
Domestic Patent References:
| JP56030915A | ||||
| JP1502185A | ||||
| JP8040880A | ||||
| JP5017356A | ||||
| JP6065078A | ||||
| JP60500867A |
Foreign References:
| WO1999006043A1 | ||||
| WO1999006044A1 |
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda