Title:
抗蠕虫性アントラキノン及びその使用方法
Document Type and Number:
Japanese Patent JP4300120
Kind Code:
B2
Abstract:
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
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Inventors:
Shike Wicks, Robert, H.
Nea, Muraled Haran, Gee., Nea
McKello, James, H.
Nea, Muraled Haran, Gee., Nea
McKello, James, H.
Application Number:
JP2003586290A
Publication Date:
July 22, 2009
Filing Date:
April 11, 2003
Export Citation:
Assignee:
Michigan State University
The Regents of The University of California
THE UNITED STATES OF AMERICA
The Regents of The University of California
THE UNITED STATES OF AMERICA
International Classes:
A61K31/122; C07H15/244; A61K31/21; A61K31/70; A61K31/704; A61P33/10; A61P33/12; C07C50/34; C07C50/38; C07C66/02; C07C69/157
Domestic Patent References:
| JP51138667A |
Foreign References:
| WO2001060971A1 |
Other References:
ANANTAPHRUTI, M. et al.,Japanese Journal of Parasitology,1982年,Vol.31, No.4,pp.321-328
RIEK, R.F. et al.,Australian Veterinary Journal,1957年,Vol.33, ,pp.169-173,Chemical Abstracts, 1957, Vol.52, p.1958, Abstract No.13114f-h
GORDON, H.M. et al.,Australian Veterinary Journal,1957年,Vol.33, 39-42,Chemical Abstracts, 1957, Vol.52, p.1958, Abstract No.13114d-e
Yun-Choi, H.S. et al.,Journal of Natural Products,1990年,Vol.53, No.3,pp.630-633
RIEK, R.F. et al.,Australian Veterinary Journal,1957年,Vol.33, ,pp.169-173,Chemical Abstracts, 1957, Vol.52, p.1958, Abstract No.13114f-h
GORDON, H.M. et al.,Australian Veterinary Journal,1957年,Vol.33, 39-42,Chemical Abstracts, 1957, Vol.52, p.1958, Abstract No.13114d-e
Yun-Choi, H.S. et al.,Journal of Natural Products,1990年,Vol.53, No.3,pp.630-633
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
Hajime Asamura
Yukihiro Ikeda
Naganuma Akio
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