Title:
口腔内速崩壊錠
Document Type and Number:
Japanese Patent JP4365095
Kind Code:
B2
Abstract:
The present invention provides an intraorally rapidly disintegrable tablet which rapidly disintegrates in the oral cavity without water and has a practical hardness, which comprises (a) a pharmacologically active ingredient with a water solubility of at least 1 mg/ml, (b) D-mannitol in the form of crystals or fine particles with primary particle average diameter of at least 30 mu m and a specific surface area of 0.4 m<2>/g or less, and (c) crospovidone.
Inventors:
Motohiro Ota
Kuboyama Noriko
Hiroichi Yoshimoto
Yasushi Watanabe
Kiyoshi Morimoto
Makoto Kosugi
Kuboyama Noriko
Hiroichi Yoshimoto
Yasushi Watanabe
Kiyoshi Morimoto
Makoto Kosugi
Application Number:
JP2002569111A
Publication Date:
November 18, 2009
Filing Date:
March 05, 2002
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
Taisho Pharmaceutical Co., Ltd.
Taisho Pharmaceutical Co., Ltd.
International Classes:
A61K9/20; A61K9/00; A61K31/165; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/26; A61K47/32; A61P9/00; A61P9/02
Domestic Patent References:
| JP2000273039A | ||||
| JP2001058944A | ||||
| JP61085330A | ||||
| JP11012162A | ||||
| JP10298061A |
Foreign References:
| WO2000057857A1 | ||||
| WO2002069933A1 |
Attorney, Agent or Firm:
Ryu Iwatani