Title:
陽イオン性表面安定剤を有する生体付着性ナノ粒子組成物
Document Type and Number:
Japanese Patent JP4394324
Kind Code:
B2
Abstract:
Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biological substrates, such as an insect, teeth, bone, nails, chitin, feathers, scales, mucous, skin, hair, plant tissue, etc. The particles may consist of pharmacologically active compounds (e.g., drug compounds for human or veterinary use), agricultural chemicals (pesticides, herbicides, fertilizers, and the like), cosmetic agents, consumer products (coloring agents, flavors, or fragrances), or other materials which function by interacting with biological substrates. In addition, the invention relates to methods of preparing and using such bioadhesive nanoparticulate compositions.
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Inventors:
Bosch, H. William
Cooper, Eugene Earl.
McGurk, Simon Elle.
Cooper, Eugene Earl.
McGurk, Simon Elle.
Application Number:
JP2001529425A
Publication Date:
January 06, 2010
Filing Date:
October 05, 2000
Export Citation:
Assignee:
Elan Pharma International, Limited
International Classes:
A61K9/14; A01N25/12; A01N25/24; A01N25/30; A61K8/04; A61K8/06; A61K8/36; A61K8/40; A61K8/41; A61K8/49; A61K8/55; A61K8/63; A61K8/73; A61K8/81; A61K31/192; A61K38/00; A61K45/00; A61K47/16; A61K47/24; A61K47/32; A61K47/36; A61K47/38; A61K49/04; A61Q5/00; A61Q5/10; A61Q19/00; A61K9/113
Domestic Patent References:
| JP6227967A |
Other References:
Colloid. Polym. Sci.,1997年,275,pp.46-53
Colloid. Polym. Sci.,1997年,275,pp.893-896
Colloid. Polym. Sci.,1997年,275,pp.893-896
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki