多発性嚢胞腎症の遺伝子分析用の組成物および方法

Title:

多発性嚢胞腎症の遺伝子分析用の組成物および方法

Document Type and Number:

Japanese Patent JP4446014

Kind Code:

B2

Abstract:

The subject invention relates to methods for detection of mutations in a PKD gene using DHPLC. The invention includes the following aspects: identification of PKD unique sites; design of PKD-specific primers; amplification of PKD-specific products; and analysis of PCR amplified products by DHPLC. The invention further relates to compositions such as identified unique sites and PKD-specific primers, and kits for performing the methods of the invention.

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Inventors:

Jeffrey George Jones
Jorge a Garces
Jin Wan
John A. Curran
Susan Kimberly Allen
Kelly Ellen Flynn
Aidan Noel Henigan
Normand Jay Robichord
Christopher M. Paratucci

Application Number:

JP2009001743A

Publication Date:

April 07, 2010

Filing Date:

January 07, 2009

Export Citation:

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Assignee:

Athena Diagnostics, Inc.

International Classes:

C12Q1/68; G01N33/53; C12N15/09; G01N33/566

Other References:

Human molecular genetics. 1999, Vol.8, No.10, p.1861-1866
Nucleic acids research. 1998, Vol.26, No.6, p.1396-1400
Genome Research. 1997, Vol.7, No.10, p.996-1005
Human mutation. 2001 Jun, Vol.17, No.6, p.439-474
Mutation research. 1993, Vol.285, No.1, p.125-144
Homo sapiens polycystic kidney disease 1 protein (PKD1) mRNA, complete cds. [online]. PRI 25-JUL-199
Homo sapiens autosomal dominant polycystic kidney disease type II protein (PKD2) gene, exon 1. [onli

Attorney, Agent or Firm:

Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo

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