Title:
Akt活性阻害薬
Document Type and Number:
Japanese Patent JP4451136
Kind Code:
B2
Abstract:
The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention
Inventors:
Linsley, Craig Davryu
Chiao, Chichiyan
Chiao, Chichiyan
Application Number:
JP2003583422A
Publication Date:
April 14, 2010
Filing Date:
April 04, 2003
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D241/40; A61K31/498; A61P35/00; A61P43/00; C07D241/36; C07D241/42; C07D401/12; C07D403/12; C07D409/12; C07D417/12; C07D471/04
Domestic Patent References:
| JP3184961A | ||||
| JP2504273A | ||||
| JP2001524545A |
Other References:
VENUGOPALAN, B., et al.,Eur. J. Med. Chem.,24(6),pp.611-614 (1989)
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura