Title:
ポリアルキレングリコール酸添加剤
Document Type and Number:
Japanese Patent JP4451308
Kind Code:
B2
Abstract:
A new class of activated polyalkylene glycol acids and their active ester reagents for conjugation to biopharmaceuticals such as polypeptides, sugars, proteins and therapeutically active small molecules to produce biologically active conjugates of these pharmaceuticals and methods for producing these conjugates.
Inventors:
Byron, Pascal Sebastian
Won, Chi-Yop
Won, Chi-Yop
Application Number:
JP2004525225A
Publication Date:
April 14, 2010
Filing Date:
July 16, 2003
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C08G65/329; A61K38/00; A61K47/34; A61K47/48; C08G65/332; C08G65/337
Domestic Patent References:
| JP62089630A | ||||
| JP63208523A | ||||
| JP2003518178A | ||||
| JP6192300A | ||||
| JP5117300A | ||||
| JP2002540065A | ||||
| JP2004533598A | ||||
| JP10067800A | ||||
| JP2000256211A |
Foreign References:
| US5672662 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda