Title:
イミダゾール誘導体
Document Type and Number:
Japanese Patent JP4490423
Kind Code:
B2
Abstract:
The present invention relates to imidazole derivatives of formula I wherein R1, R2, R3, R4, X, Y and R are described hereinabove, or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition comprising the imidazole derivatives of formula I, a process for preparing a compound of formula I, and a method of treating or preventing acute and/or chronic neurological disorder comprising administering to a patient in need of such treatment and/or prevention a therapeutically effective amount of said pharmaceutical composition. These disorders include Alzheimer's disease. These disorders also include mild cognitive impairment.
Inventors:
Buttelmann, Bernd
Ceccarelli, Simona Maria
Jaschke, Georg
Korzewski, Sabine
Richard Hugh Philip, Porter
Eric, Fieira
Ceccarelli, Simona Maria
Jaschke, Georg
Korzewski, Sabine
Richard Hugh Philip, Porter
Eric, Fieira
Application Number:
JP2006525079A
Publication Date:
June 23, 2010
Filing Date:
August 27, 2004
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D401/06; A61K31/4439; A61K31/444; A61P1/08; A61P9/00; A61P9/02; A61P9/10; A61P13/02; A61P21/02; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/32; A61P25/34; A61P25/36; A61P27/02; A61P43/00; C07D401/14
Domestic Patent References:
| JP2009500291A | ||||
| JP2003508390A | ||||
| JP4506522A |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda