Title:
Rho-キナーゼ阻害剤
Document Type and Number:
Japanese Patent JP4505228
Kind Code:
B2
Abstract:
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
Inventors:
Danaparan Nagaratnam
Udai Kire
Davod Asgari
Janshin Xiao
Xiao-Gao Liu
Wang Chung Guang
Barry Heart
Olaf Weber
Mark Lynch
Jean Ray
One Ray
Udai Kire
Davod Asgari
Janshin Xiao
Xiao-Gao Liu
Wang Chung Guang
Barry Heart
Olaf Weber
Mark Lynch
Jean Ray
One Ray
Application Number:
JP2003560016A
Publication Date:
July 21, 2010
Filing Date:
January 10, 2003
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07D471/04; C07D491/048; A61K31/519; A61K31/5377; A61P7/02; A61P9/10; A61P9/12; A61P11/06; A61P15/10; A61P19/10; A61P25/00; A61P27/06; A61P35/00; A61P43/00; C07D491/04; C07D495/04
Foreign References:
| WO2001009134A1 | ||||
| WO1998002438A1 | ||||
| WO1999065908A1 | ||||
| WO1997032882A1 | ||||
| WO1996040142A1 | ||||
| WO1999024440A1 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Yasuo Shibata
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Yasuo Shibata