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Title:
医薬物質としての新規ピロール誘導体
Document Type and Number:
Japanese Patent JP4519407
Kind Code:
B2
Abstract:
Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S

Inventors:
Jason Scott Sawyer
Douglas Wade Bait
Paola Cappetti
Todd vincent decoro
Alexander Glen Godfrey
Theodore Goodson Jr.
David Kent Heron
Lee Hong-You
Liao Junkai
William Thomas McMillen
Sean Christopher Miller
Nicholas Anthony Mort
Jonathan Michael Ingling
Edward Sea Earl Smith
Application Number:
JP2002591506A
Publication Date:
August 04, 2010
Filing Date:
May 13, 2002
Export Citation:
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Assignee:
Eli Lilly and Company
International Classes:
C07D487/04; A61K31/4439; A61K31/444; A61K31/4709; A61K31/496; A61K31/5383; A61K31/55; A61K45/00; A61P3/10; A61P7/04; A61P9/10; A61P13/12; A61P17/02; A61P17/12; A61P19/02; A61P21/02; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/18; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D401/12; C07D471/04; C07D498/04
Foreign References:
WO2001016138A1
Other References:
Tetrahedron Letters,1983年,Vol.24, No.10,p1067-1070
Bulletin des Societes Chimiques Belges,1986年,Vol.95, No.8,p655-662
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Minato Saito