Title:
選択的糖質コルチコイド受容体調節剤としてのオクタヒドロ-2-H-ナフト[1,2-f]インドール-4-カルボキサミド誘導体
Document Type and Number:
Japanese Patent JP4520309
Kind Code:
B2
Abstract:
The present invention encompasses compounds of Formula I: or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
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Inventors:
Ali, Amjiyad
Astor, Susan Day
Barkovec, The Ames M
Donald Davour, Graham
Hunt, The Julianne A
Karasi, Florida
Sinclair, Peter Theei
Tata, The A's Earl
Taylor, Gale E
Gure, Ji Yun El
Astor, Susan Day
Barkovec, The Ames M
Donald Davour, Graham
Hunt, The Julianne A
Karasi, Florida
Sinclair, Peter Theei
Tata, The A's Earl
Taylor, Gale E
Gure, Ji Yun El
Application Number:
JP2004568945A
Publication Date:
August 04, 2010
Filing Date:
September 17, 2003
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D231/54; A61K31/4162; C07D231/44; C07D417/00; A61K31/416; A61P43/00; A61K
Foreign References:
| US4349558 | ||||
| US4307102 | ||||
| CA1178965A1 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura