Title:
超水和シチコリン、プロセスおよび使用
Document Type and Number:
Japanese Patent JP4530534
Kind Code:
B2
Abstract:
A hyperhydrated form of citicoline and its formulations, which exhibits desirable characteristics, including crystal formation, moisture resistance, improved storage stability, and formulation versatility, is disclosed. Methods of preparing the citicoline hyperhydrate and its use in the manufacture of stable pharmaceutical dosage forms are also described.
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Inventors:
Larch, Gregory Etch.
Application Number:
JP2000526231A
Publication Date:
August 25, 2010
Filing Date:
December 23, 1998
Export Citation:
Assignee:
Fuerrel International, Sociedad Anonima
International Classes:
C07H19/10; A01N43/04; A61K9/20; A61K9/48; A61K31/7042; A61K31/7052; A61K31/7064; A61K31/7068; A61P9/00; A61P9/10; A61P25/00
Domestic Patent References:
JP47019017A | ||||
JP52003945B1 | ||||
JP62129296A | ||||
JP47001901A |
Foreign References:
WO1996027380A1 |
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda