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Title:
糖尿病治療のためのピペリジノピリミジンジペプチジルペプチダーゼ阻害剤
Document Type and Number:
Japanese Patent JP4530852
Kind Code:
B2
Abstract:
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

Inventors:
Masvink, Robert Theei
Scott Day, Edmondson
Ann, Yee
Application Number:
JP2004521700A
Publication Date:
August 25, 2010
Filing Date:
July 11, 2003
Export Citation:
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Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D471/04; A61K31/519; A61P1/00; A61P1/02; A61P1/18; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P5/28; A61P5/50; A61P9/08; A61P9/10; A61P9/12; A61P13/08; A61P13/12; A61P19/10; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
JP10182613A
JP6321944A
JP2006516573A
Foreign References:
US5281602
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura