Title:
重合体-白金化合物
Document Type and Number:
Japanese Patent JP4536165
Kind Code:
B2
Abstract:
A polymer-platinum compound for use in tumor treatment is described. The compound is composed of a polymer backbone having platinum-containing side chains spaced along the polymer backbone. The side chains are composed of an oligopeptide attached at one end to the backbone and at the other end to the platinum compound.
Inventors:
Duncan, Ruth
Eva Gorou, Eva Goras.
Buckley, Robert G.
The Anasi, Elisabetta
Eva Gorou, Eva Goras.
Buckley, Robert G.
The Anasi, Elisabetta
Application Number:
JP54608398A
Publication Date:
September 01, 2010
Filing Date:
April 15, 1998
Export Citation:
Assignee:
Access Pharmaceuticals, Incorporated
International Classes:
A61K47/48; A61K31/282; A61K33/24; A61K47/32; A61K47/42; A61P35/00
Other References:
DUNCAN,R. et al, Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro, Br J Cancer, 1987年, Vol.55, No.2, p.165-74
SCHECHTER,B. et al, Soluble polymers as carriers of cis-platinum, J Control Release, 1989年, Vol.10, p.75-87
NEUSE,EW. et al, cis-Diaminedichloroplatinum(II) complexes reversibly bound to water-soluble polyaspartamide carriers for chemotherapeutic applications. I. Platinum coodination to preformed, carrier-attached ethylenediamine ligands, J Inorg Organomet Polym, 1991年, Vol.1, No.2, p.147-165
SCHECHTER,B. et al, Soluble polymers as carriers of cis-platinum, J Control Release, 1989年, Vol.10, p.75-87
NEUSE,EW. et al, cis-Diaminedichloroplatinum(II) complexes reversibly bound to water-soluble polyaspartamide carriers for chemotherapeutic applications. I. Platinum coodination to preformed, carrier-attached ethylenediamine ligands, J Inorg Organomet Polym, 1991年, Vol.1, No.2, p.147-165
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita