Title:
病原体不活化のための脆い化合物
Document Type and Number:
Japanese Patent JP4551502
Kind Code:
B2
Abstract:
Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivating pathogens in biological materials such as red blood cell preparations and plasma. The compounds and methods may be used to treat materials intended for in vitro or in vivo use, such as clinical testing or transfusion. The compounds are designed to specifically bind to and react with nucleic acid, and then to degrade to form breakdown products. The degradation reaction is preferably slower than the reaction with nucleic acid.
Inventors:
Cook, david
Merit, john
Nerio, Irene
Lapoport, Henry
Stasinopoulos, Adonis
Wollowitz, Susan
Matejovik, Jean
Merit, john
Nerio, Irene
Lapoport, Henry
Stasinopoulos, Adonis
Wollowitz, Susan
Matejovik, Jean
Application Number:
JP53119998A
Publication Date:
September 29, 2010
Filing Date:
January 06, 1998
Export Citation:
Assignee:
Celus Corporation
International Classes:
C07D219/10; A01N1/00; A01P1/00; A61K35/14; A61L2/00; A61M1/02; B01J20/28; C07D405/12; C07D493/04; C07F9/64; C07F9/6561
Foreign References:
| WO1996039818A1 |
Other References:
Journal or Medicinal Chemistry, 1990年, vol.33, 1177-1186
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita