Title:
IL-18BPに結合でき、第2サイトカインの活性を阻害するサイトカインの使用
Document Type and Number:
Japanese Patent JP4563813
Kind Code:
B2
Abstract:
The present invention relates to the use of a cytokine-1, preferably from the IL-1 family more preferably IL-1F7b, or an isoform, mutein, fused protein, functional derivative or fragment thereof capable of binding to IL-18BP or a mutein, fused protein, functional derivative or fragment thereof and capable of inhibiting a receptor of a cytokine-2, cytokine-2 being a member of the IL-1 family, preferably IL-18, in the manufacture of a medicament for the treatment or prevention of a disease which is caused or aggravated by inducing said receptor of cytokine-2.
Inventors:
Dinalero, Charles A
Kim, Seo-Hyun
Buchler, Philip
Kim, Seo-Hyun
Buchler, Philip
Application Number:
JP2004543122A
Publication Date:
October 13, 2010
Filing Date:
October 03, 2003
Export Citation:
Assignee:
Ares Trading Society Anonym
International Classes:
A61K38/00; A61K35/76; A61K38/17; A61K38/19; A61K38/20; A61K48/00; A61P1/04; A61P19/02; A61P29/00; A61P43/00; C07K14/545
Domestic Patent References:
| JP2001514876A | ||||
| JP6503320A | ||||
| JP2002179590A |
Foreign References:
| WO2000063226A1 | ||||
| WO2001007480A1 |
Other References:
KUMAR, S., et al.,CYTOKINE,2002年 4月21日,Vol.18, No.2,p.61-71
Attorney, Agent or Firm:
Kawamura Taku
Yousuke Fujimori
Seiji Tani
Fumio Akiyama
Yousuke Fujimori
Seiji Tani
Fumio Akiyama