Title:
低可溶性分子を可溶化するための新しい非イオン性界面活性剤
Document Type and Number:
Japanese Patent JP4589917
Kind Code:
B2
Abstract:
New non-ionic surfactants in the form of polyoxyalkylene glycol hydroxy fatty acid derivatives or monoalkylated polyoxyalkylene glycol hydroxy fatty acid derivatives having a polyoxyalkylene/alkyl polyoxyalkylene chain with a chain-length of 25-455 repeating units and a specified substituent on the hydroxy position of the specified hydroxy fatty acid, according to the general formula (I) CH3-(CH2)x-CH-(CH2)y-CO-[-O-R3-]z-O-R1 R2-O (I); wherein for example R1 is methyl, R2 is optionally substituted C14-C22 acyl, alkyl, or alkenyl, R3 is ethylene, x is 2-12, y is 7-17, (x+y) is 3-19 and z is 25-57; advantageously prepared by involving an enzymatic process, formulations comprising them, their use as solubilizers and a process involving a hydrolytic enzyme for preparing them.
Inventors:
Christian von Korswand
Karl Furth
Eric Soderlind
Fredrick Vicklund
Karl Furth
Eric Soderlind
Fredrick Vicklund
Application Number:
JP2006508018A
Publication Date:
December 01, 2010
Filing Date:
April 13, 2004
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
C08G65/331; A61K9/00; A61K9/02; A61K9/20; A61K9/48; A61K47/14; A61K47/34; C07C69/708; C08G65/332; C12P7/62
Domestic Patent References:
| JP2000143544A | ||||
| JP9157386A | ||||
| JP9253406A | ||||
| JP55133331A | ||||
| JP2000515174A | ||||
| JP61187795A |
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Mitsutaka Iwasaki
Shoji Nakajima