Title:
抗OX40L抗体
Document Type and Number:
Japanese Patent JP4594986
Kind Code:
B2
Abstract:
This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from inflammatory diseases.
Inventors:
Endor, joseph
Eugi, Elsey
Fuentes, Maria
Grouse, Ivo
Love Rain, Alan
Lanzenafel, Martin
Parlen, Paul
Revels, Frank
Schumacher, Ralph
Zeber, Stephan
Van de Winkel, Yang
Fan houst, martin
Eugi, Elsey
Fuentes, Maria
Grouse, Ivo
Love Rain, Alan
Lanzenafel, Martin
Parlen, Paul
Revels, Frank
Schumacher, Ralph
Zeber, Stephan
Van de Winkel, Yang
Fan houst, martin
Application Number:
JP2007531688A
Publication Date:
December 08, 2010
Filing Date:
September 16, 2005
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12N15/09; A61K39/395; A61P11/06; A61P19/02; A61P29/00; A61P37/06; A61P37/08; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
Foreign References:
| WO2003059245A2 | ||||
| WO1999058572A1 |
Other References:
J. Immunol.,2001年 2月 1日,Vol.166, No.3,pp.2108-2015
J. Virol.,2001年12月,Vol.75, No.24,pp.12161-12168
Immunology today,1993年,Vol.14, No.6,pp.243-246
Journal of Molecular Biology,1992年,Vol.224, No.2,pp.487-499
J. Virol.,2001年12月,Vol.75, No.24,pp.12161-12168
Immunology today,1993年,Vol.14, No.6,pp.243-246
Journal of Molecular Biology,1992年,Vol.224, No.2,pp.487-499
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito