Title:
アミド誘導体
Document Type and Number:
Japanese Patent JP4595059
Kind Code:
B2
Abstract:
A medicament for enhancing an effect of a cancer therapy based on a mode of action of DNA injury, which comprises as an active ingredient a compound represented by the following general formula (I) or a salt thereof: wherein one of R1 and R2 represents hydrogen atom and the other represents the formula -X-A wherein A represents hydrogen atom or an acyl group, X represents oxgen atom or NH; one of R3 and R4 represents hydrogen atom and the other represents the following formula: wherein Y represents a sulfonyl group or a carbonyl group, R5 represents a cyclic group, Z represents a single bond or a C1 to C4 alkylene group, R6 represents hydrogen atom or a C1 to C6 alkyl group.
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Inventors:
Susumu Muto
Akiko Itai
Akiko Itai
Application Number:
JP2003583397A
Publication Date:
December 08, 2010
Filing Date:
April 18, 2003
Export Citation:
Assignee:
Pharmaceutical Molecular Design Laboratory Co., Ltd.
International Classes:
A61K31/18; A61K31/166; A61K31/167; A61K31/22; A61K31/222; A61K31/255; A61K31/341; A61K31/36; A61K31/407; A61K31/4184; A61K31/4402; A61K38/00; A61K45/00; A61P35/00; A61P43/00; C07C237/48; C07C311/29; C07C311/39; C07C311/40; C07D213/42; C07D213/53; C07D235/14; C07D307/52; C07D317/06; C07D235/10
Domestic Patent References:
JP2001504492A | 2001-04-03 | |||
JP2002501043A | 2002-01-15 | |||
JPS4830733A | 1973-04-23 | |||
JPH03217459A | 1991-09-25 | |||
JP2004520394A | 2004-07-08 | |||
JP2005525357A | 2005-08-25 |
Foreign References:
US5378715A | 1995-01-03 | |||
US5399487A | 1995-03-21 | |||
WO1996040641A1 | 1996-12-19 | |||
WO2000046189A1 | 2000-08-10 | |||
US0827446A1 | ||||
WO2000042213A1 | 2000-07-20 | |||
WO2003070691A1 | 2003-08-28 | |||
WO2003007931A1 | 2003-01-30 |
Attorney, Agent or Firm:
Isshiki International Patent Service Corporation