Title:
非球形シームレスカプセルの製造装置
Document Type and Number:
Japanese Patent JP4634796
Kind Code:
B2
Abstract:
In manufacturing an aspherical seamless capsule comprises, firstly, a seamless capsule C1 having a filler encapsulated with a shell membrane is provided, then it is dried in a dryer 12 until a predetermined percentage content of solvent in the shell membrane reaches a predetermined value. Subsequently, the seamless capsule is heated by a heater 38 so that the shell material may get to a semi-sol state. Then, the heated seamless capsule is formed into an aspherical shape using a forming machine such as a compression molding machine. Because the spherical seamless capsule has a shell membrane which is dried to get semi-sol so that it may have a reduced elasticity and a shortened stress relaxation time, the capsule can be formed in a short time and suppressed from restoring to the original spherical shape. The semi-sol shell membrane has almost no change in properties, and so allows easiness in temperature control for treatment. The aspherical capsule after being formed does not or rarely need drying, resulting in wrinkle resistance and little variation in shape brought on the surface of the shell membrane.
Inventors:
Takeshi Nakamura
Toshinari Taira
Kenta Wada
Katsuya Otomo
Toshinari Taira
Kenta Wada
Katsuya Otomo
Application Number:
JP2004515539A
Publication Date:
February 16, 2011
Filing Date:
June 20, 2003
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
A61J3/07; A61K9/48; B01J13/14; B01J13/20; B29C43/02; B29C43/20
Domestic Patent References:
| JP2000325431A | 2000-11-28 | |||
| JPH0810313A | 1996-01-16 | |||
| JPH0655060A | 1994-03-01 | |||
| JP2001009267A | 2001-01-16 | |||
| JPS6046981B2 | 1985-10-18 |
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshiki Kuroki
Shiro Terasaki
Yoshiki Kuroki
Shiro Terasaki