Title:
新規なスピロベンゾフランラクタムおよびその誘導体、その製造方法、ならびにその使用
Document Type and Number:
Japanese Patent JP4638737
Kind Code:
B2
Abstract:
Spirobenzofuran-lactam derivatives (I) and their salts are new. Spirobenzofuran-lactam derivatives of formula (I) and their salts are new. R1 and R2 = hydrogen, 1-6C alkyl, 2-6C alkenyl or alkynyl, 5-14 C aryl, all optionally substituted by 1-3 of hydroxy, oxo, 1-6C alkoxy, 2-6C alkenyloxy, 5-14C aryloxy, 1-6C alkylamino, 2-6C alkenylamino, 1-6C alkylcarbonylamino, 5-14C arylcarbonylamino, amino or halo; R3 = hydroxy, OR1 or NHR1; and R4 = hydrogen, 1-6C alkyl, 2-6C alkenyl, 5-14C aryl or 1-6C alkyl(5-14C) aryl. Independent claims are also included for the following: (1) preparing (I) by fermenting Stachybotris atra ST 002348 (DSM 14952); and (2) Stachybotris atra ST 002348 (DSM 14952) as new.
Inventors:
Claudia Ader
Michael Kurz
Luigi Torti
Michael Kurz
Luigi Torti
Application Number:
JP2004559733A
Publication Date:
February 23, 2011
Filing Date:
December 01, 2003
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
C12P17/18; A61K31/407; A61P3/10; A61P7/02; A61P9/00; A61P9/02; A61P9/04; A61P9/10; A61P11/00; A61P35/00; C07D491/107; C07D493/04; C12N1/14; C12R1/645
Domestic Patent References:
| JP10251262A | ||||
| JP6184181A |
Other References:
J. Antibiot.,1996年 1月,Vol.49, No.1,pp.13-19
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa