Title:
L-カルニチン生合成関連遺伝子を含む腸内細菌属微生物、およびその微生物を用いたL-カルニチンの産生方法
Document Type and Number:
Japanese Patent JP4639235
Kind Code:
B2
Abstract:
Provided is a microorganism belonging to the family Enterobacteriaceae including: a polynucleotide encoding N-trimethyllysine hydroxylase activity derived from Neurospora crassa; a polynucleotide encoding 3-hydroxy-6-N-trimethyllysine aldolase activity derived from Neurospora crassa; a polynucleotide encoding γ-trimethylaminoaldehyde dehydrogenase activity derived from Neurospora crassa; and a polynucleotide encoding γ-butyrobetaine hydroxylase activity derived from Neurospora crassa. Provided is also a process for producing L-carnitine using the microorganism.
Inventors:
Lee Belong-Uke
Kang Wan-Ku
Park Young-Hahn
Koo Yun-Sun
Chun Sang-Oh
Juja-Yeong
Kang Wan-Ku
Park Young-Hahn
Koo Yun-Sun
Chun Sang-Oh
Juja-Yeong
Application Number:
JP2007542880A
Publication Date:
February 23, 2011
Filing Date:
July 19, 2005
Export Citation:
Assignee:
CJ CheilJedang Corporation
International Classes:
C12N15/09; C12N1/21; C12P13/00
Domestic Patent References:
| JP2003125779A | ||||
| JP2007525221A |
Foreign References:
| WO1995018220A1 | ||||
| WO2005049692A1 |
Other References:
FEMS Microbiol. Lett.,2002年,vol.210, no.1,pp.19-23
Nucleic Acids Res.,2003年,vol.31, no.7,pp.1944-1954
Nature,2003年,vol.422, no.6934,pp.859-868
Nucleic Acids Res.,2003年,vol.31, no.7,pp.1944-1954
Nature,2003年,vol.422, no.6934,pp.859-868
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki