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Title:
複合体混合物中に溶解されたいくつかの分子ターゲットを分離し、および、または解析する装置
Document Type and Number:
Japanese Patent JP4659748
Kind Code:
B2
Abstract:
The apparatus for the detection and/or separation of a number of molecular targets, in a solution of a complex mixture, has a matrix (2) of micro-columns each with an immobilized molecular probe for a specific bonding with a target molecule. An upper (3) network of capillaries delivers the complex mixture to the micro-columns by a plunger (6) from a lateral channel (31). The apparatus for the detection and/or separation of a number of molecular targets, in a solution of a complex mixture, has a matrix (2) of micro-columns each with an immobilized molecular probe for a specific bonding with a target molecule. An upper (3) network of capillaries delivers the complex mixture to the micro-columns by a plunger (6) from a lateral channel (31). A second capillary network (4), linked to a secondary lateral channel (7), carries the target molecules after elution through a channel (41) towards one or more detectors (5) e.g. a mass spectrometer, for recovery and/or analysis.

Inventors:
Ugorin, Nikola
Schbilard, Silvie
Ori, Catherine
Le Beau, Jerome
Application Number:
JP2006527437A
Publication Date:
March 30, 2011
Filing Date:
August 27, 2004
Export Citation:
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Assignee:
Comisaria a Renergie Atomique
International Classes:
G01N33/543; B01J19/00; B01L3/00; C12M1/34; C12Q1/68; G01N27/62; G01N33/53; G01N37/00; C12N15/09; G01N21/27
Foreign References:
WO2004059301A1
US20020090649
Attorney, Agent or Firm:
Satoshi Kono
Makoto Nakamura
Kurata Masatoshi
Takashi Mine
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Nobuhisa Nogawa
Ryo Hashimoto
Tetsuya Kazama