Title:
スフェロイド、その製造方法および医薬組成物
Document Type and Number:
Japanese Patent JP4660192
Kind Code:
B2
Abstract:
The invention relates to a directly-compressible gastro-resistant spheroid. The spheroid comprises: (i) a core containing one or more active substances; (ii) a flexible, deformable film which directly coats the aforementioned core and which comprises an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides, the fatty acids of which include at least 8 carbon atoms; and (iii) an outer water-dispersible layer containing at least one disintegrating agent. The invention further relates to multiparticular tablets comprising said spheroids.
Inventors:
Philip and Chenouviere
Dominique, Marshall
Dominique, Marshall
Application Number:
JP2004540887A
Publication Date:
March 30, 2011
Filing Date:
October 03, 2003
Export Citation:
Assignee:
ETHYPHARM
International Classes:
A61K47/14; A61K9/16; A61K9/20; A61K9/22; A61K9/50; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38
Domestic Patent References:
| JP2003500358A | ||||
| JP2002501895A | ||||
| JP9502740A | ||||
| JP2004508396A |
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeyasu Ito
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Takeyasu Ito