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Title:
三元組成物の調製のための混合粉砕方法
Document Type and Number:
Japanese Patent JP4679898
Kind Code:
B2
Abstract:
A ternary composition comprising an active substance, a hydrophilic or hydrophobic carrier and a co-grinding auxiliary substance and a process for the preparation thereof by the co-grinding of the thee components, in which said process allows operating with drastically reduced co-grinding times with respect to the known art and to obtain ternary compositions in which the active substance shows characteristics of amorphisation, solubility and dissolution speed as requested for the various uses.

Inventors:
Carli, Fabio
Corbi Mora, Paolo
Canal, Tiziana
Application Number:
JP2004505011A
Publication Date:
May 11, 2011
Filing Date:
May 19, 2003
Export Citation:
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Assignee:
Actimex Society A Responsor Billitas Limitata
International Classes:
A61K9/14; A23L1/00; A23L27/21; A23P1/02; A61K8/02; A61K8/30; A61K8/34; A61K8/35; A61K8/36; A61K8/365; A61K8/41; A61K8/44; A61K8/63; A61K8/72; A61K8/73; A61K8/81; A61K9/48; A61K38/00; A61K45/08; A61K47/12; A61K47/18; A61K47/22; A61K47/32; A61K47/36; A61K47/38; A61K47/40; A61K47/44; A61Q17/04; A61Q19/00; A61Q19/08; A61K31/05; A61K31/198; A61K31/235; A61K31/5685; A61K31/57; A61K31/573; A61P9/00; A61P11/14; A61P31/04; A61P43/00
Domestic Patent References:
JP2001518083A
JP63115821A
JP2001513563A
JP56133217A
Foreign References:
WO2000037109A1
WO2000015261A1
Other References:
MURA,P. et al,The influence of polyvinylpyrrolidone on naproxen complexation with hydroxypropyl-beta-cyclodextrin,Eur J Pharm Sci,2001年,Vol.13, No.2,p.187-194
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Yutaka Nagata
Tsutomu Toyama