Title:
早期翻訳終結およびナンセンス媒介性RNA崩壊を阻害する化合物を検定する方法
Document Type and Number:
Japanese Patent JP4683808
Kind Code:
B2
Abstract:
The present application provides methods of assaying for compounds that inhibit premature translation termination and nonsense mediated RNA decay in cells.
Inventors:
Holger Beckman
Mark Learn
Stuart Peltz
Kevin Chaplinski
Mark Learn
Stuart Peltz
Kevin Chaplinski
Application Number:
JP2001545593A
Publication Date:
May 18, 2011
Filing Date:
December 13, 2000
Export Citation:
Assignee:
PTC THERAPEUTICS, INC.
International Classes:
C12N15/09; G01N33/50; C12Q1/02; C12Q1/66; C12Q1/68; G01N33/15; G01N33/53; G01N33/58; C12Q1/34; C12Q1/48; C12Q1/56
Foreign References:
| WO1999020797A1 | ||||
| US5641627 |
Other References:
Cell, vol. 96, pages 307-310 (1999)
Trends Biochem. Sci., vol. 21, pages 433-438 (1996)
Trends Biochem. Sci., vol. 21, pages 433-438 (1996)
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura
Kyousei Tamura