Title:
新規ポリペプチド
Document Type and Number:
Japanese Patent JP4689047
Kind Code:
B2
Abstract:
According to the present invention, there can be provided a novel polypeptide having beta 1,3-galactosyltransferase activity involved in the synthesis of type 1 sugar chains, a DNA coding for said polypeptide, a recombinant vector comprising said DNA, a transformant carrying said recombinant vector, a process for producing type 1 sugar chain-containing sugar chains and complex carbohydrates by use of said polypeptide or said transformant, an antibody recognizing said polypeptide, a method for detecting or quantifying said polypeptide by use of said antibody, a method for screening a substance correlated with said polypeptide, a method for diagnosis or treatment of cancers in the digestive system by use of said DNA or said antibody, and a method for treatment of cancers in the digestive system by use of a substance obtained by said screening method.
Inventors:
Hisashi Narimatsu
Soichiro Isshiki
Akira Kaguya
Katsutoshi Sasaki
Soichiro Isshiki
Akira Kaguya
Katsutoshi Sasaki
Application Number:
JP2000601172A
Publication Date:
May 25, 2011
Filing Date:
February 24, 2000
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
International Classes:
C12N15/09; A01H5/00; A01K67/027; C12N1/21; C12N5/00; C12N5/10; C12N9/10; C12N15/54; C12P19/00; C12P19/04; C12P21/02; C12P21/08; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/574; A61K38/00; A61K39/00; C12R1/185; C12R1/91
Other References:
JPN6010000145, Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ．，Ｊａｎ．，１９９９，Ｖｏｌ．９６，Ｎｏ．２ ｐ．４０６−４１１
JPN6010000146, Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９８，Ｖｏｌ．２７３，Ｎｏ．２１，ｐ．１２７７０−１２７７８
JPN6010000146, Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９８，Ｖｏｌ．２７３，Ｎｏ．２１，ｐ．１２７７０−１２７７８