Title:
中枢神経系疾患の治療において有用な1-アリールスルホニル-3-置換インドール及びインドリン誘導体
Document Type and Number:
Japanese Patent JP4694129
Kind Code:
B2
Abstract:
The present invention relates to 1-arylsulfonyl-3 substituted indole or indoline derivatives having the general formula (I) (I) wherein the dotted line represents an optional bond; n is 0 or 1; m is 0-5 and Ar, R6-R11 are defined in the description. The invention further relates to pharmaceutical compositions comprising said derivatives, and to the use of these 1-arylsulfonyl-3-substituted indole or indoline derivatives in the treatment of central nervous disorders such as psychosis, schizophrenia, manic depressions, depressions, neurological disorders, cognitive enhancement, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's disease.
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Inventors:
Spinks, daniel
Armor, Little Y
Miller, David The Ray
Rankovich, Zoran
Spinks, Gale
Mestress, jjorday
Jap, David Robert
Armor, Little Y
Miller, David The Ray
Rankovich, Zoran
Spinks, Gale
Mestress, jjorday
Jap, David Robert
Application Number:
JP2003567402A
Publication Date:
June 08, 2011
Filing Date:
February 05, 2003
Export Citation:
Assignee:
Narmrose Fuennault Chap Organon
International Classes:
C07D209/18; C07D487/04; A61K31/40; A61K31/404; A61K31/433; A61K31/4439; A61K31/454; A61K31/4545; A61K31/46; A61K31/496; A61K31/497; A61K31/551; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P43/00; C07D209/42; C07D401/06; C07D401/12; C07D401/14; C07D403/06; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/14; C07D417/12; C07D417/14; C07D451/02
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura