Title:
ウサギ由来のIgG抗体に結合性を有する核酸分子
Document Type and Number:
Japanese Patent JP4698559
Kind Code:
B2
Abstract:
The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (K D ) of 1.18 × 10 -7 (M) or less to the rabbit IgG antibody.
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Inventors:
Yoshida Yoshihito
Furuichi Makio
Iwao Waga
Hiroshi Mizuno
Furuichi Makio
Iwao Waga
Hiroshi Mizuno
Application Number:
JP2006317113A
Publication Date:
June 08, 2011
Filing Date:
November 24, 2006
Export Citation:
Assignee:
NEC Soft Co., Ltd.
International Classes:
C12N15/09; C12N15/115; G01N33/53
Domestic Patent References:
| JP6508022A | ||||
| JP2003506024A |
Other References:
J. Immunol. Methods, (2005), Vol.296, p.45-62
Anal Chem., (2004), Vol. 76, No. 18, p. 5387-5392.
Anal Chem., (2004), Vol. 76, No. 18, p. 5387-5392.
Attorney, Agent or Firm:
Koichiro Tsujimaru
Yumi Nakayama
Reiko Yoshida
Isaji So
Yumi Nakayama
Reiko Yoshida
Isaji So