Title:
2-メトキシメチル-3-(3,4-ジクロロフェニル)-8-アザビシクロ[3.2.1]オクタン酒石酸塩
Document Type and Number:
Japanese Patent JP4711961
Kind Code:
B2
Abstract:
This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts, such as L-tartrate monohydrates and anhydrates, wherein the salts are useful as monoamine neurotransmitter re-uptake inhibitors. Additionally, the invention also relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention.
Inventors:
Frost Loop, Brian
Wetchen, Frank
Jensen, Klaus, and Snai
Wetchen, Frank
Jensen, Klaus, and Snai
Application Number:
JP2006521585A
Publication Date:
June 29, 2011
Filing Date:
July 29, 2004
Export Citation:
Assignee:
Neurosearch Actizel Scab
International Classes:
C07D451/02; A61K31/439; A61P1/00; A61P3/04; A61P13/02; A61P15/00; A61P19/02; A61P21/00; A61P25/00; A61P25/02; A61P25/06; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P29/00; A61P43/00; C07C59/255
Domestic Patent References:
| JP2000504739A |
Other References:
岡野定舗著「新・薬剤学総論(第3版)」(1987年),(株)南江堂,109-111,256-257,327頁
ABDOU H M.,DISSOLUTION, BIOAVAILABILITY AND BIOEQUIVALENCE,米国,MACK PUBLISHING CO.,P53-73
ABDOU H M.,DISSOLUTION, BIOAVAILABILITY AND BIOEQUIVALENCE,米国,MACK PUBLISHING CO.,P53-73
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda