Title:
キナゾリンカリウムチャネル阻害剤
Document Type and Number:
Japanese Patent JP4719681
Kind Code:
B2
Abstract:
The present invention relates to compounds useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like.
Inventors:
Trotter, Be Wesley
Isaaccus, Litchiard
Isaaccus, Litchiard
Application Number:
JP2006528071A
Publication Date:
July 06, 2011
Filing Date:
September 17, 2004
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D239/88; C07D239/90; C07D239/96; C07D471/04; C07D487/04; A61K31/517; A61K31/519; A61K31/55; A61K45/00; A61P7/02; A61P9/04; A61P9/06; A61P9/10; A61P37/06; A61P43/00
Other References:
CHOI, B. H. et al,Direct inhibition of the cloned Kv1.5 channel by AG-1478, a tyrosine kinase inhibitor,American Journal of Physiology Cell Physiology,2002年,vol.282, no.6,p.C1461-C1468
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura