Title:
マロンアミド誘導体
Document Type and Number:
Japanese Patent JP4750701
Kind Code:
B2
Abstract:
The present invention relates to malonamide derivatives of formula A-D-B-1, as inhibitors of raf-kinase and the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition.
Inventors:
Bruges, David
Buchstaller, Hans-Peter
Wiesner, Matthias
Finzinger, Dirk
Baumgart, Manfred
Sillenberg, Christian
Tsuenke, Frank
Amento, Christiana
Grell, Matthias
Buchstaller, Hans-Peter
Wiesner, Matthias
Finzinger, Dirk
Baumgart, Manfred
Sillenberg, Christian
Tsuenke, Frank
Amento, Christiana
Grell, Matthias
Application Number:
JP2006518009A
Publication Date:
August 17, 2011
Filing Date:
June 18, 2004
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D213/40; A61P35/00; C07C233/15; C07D213/38; C07D213/65; C07D213/66; C07D213/68; C07D213/75; C07D213/79; C07D213/81; C07D261/14; C07D413/12; A61K31/4406; A61K31/4409; A61K31/4439; A61P1/04; A61P1/16; A61P3/00; A61P3/10; A61P7/02; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P11/06; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/02; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P35/02; A61P37/02; A61P37/04; A61P37/06; A61P43/00
Domestic Patent References:
| JP2000053570A | 2000-02-22 | |||
| JPH08295667A | 1996-11-12 | |||
| JPH06172279A | 1994-06-21 | |||
| JP2002528533A | 2002-09-03 | |||
| JP2001526220A | 2001-12-18 |
Foreign References:
| WO2002044126A2 | 2002-06-06 | |||
| WO2003000660A1 | 2003-01-03 | |||
| WO2000042012A1 | 2000-07-20 | |||
| WO2001087309A1 | 2001-11-22 | |||
| WO2004002481A1 | 2004-01-08 | |||
| WO2004058234A2 | 2004-07-15 |
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata