Title:
ミクロソームワクチン
Document Type and Number:
Japanese Patent JP4903043
Kind Code:
B2
Abstract:
A vaccine composition is provided which comprises inverted microsomes or fragments thereof from an animal cell in association with an externally disposed peptide antigen and a protein of the MHC.
Inventors:
One Ping
Leash ring
Leash ring
Application Number:
JP2006522392A
Publication Date:
March 21, 2012
Filing Date:
July 30, 2004
Export Citation:
Assignee:
Queen Mary and Westfield College
International Classes:
A61K39/00; A61K39/12; A61K39/385; A61P31/00; A61P35/00; A61P37/00
Domestic Patent References:
| JP2002527467A | ||||
| JP3505731A | ||||
| JP6507168A |
Foreign References:
| WO2001096377A1 | ||||
| WO2002030964A1 | ||||
| US20020122820 |
Other References:
PAULSSON,K. et al,Chaperones and folding of MHC class I molecules in the endoplasmic reticulum,Biochim Biophys Acta,2003年,Vol.1641, No.1,p.1-12
DE,L.E. et al,Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies,J Cell Biol,1987年,Vol.104, No.2,p.209-19
HUGHES,L.E. et al,A study in clinical cancer immunotherapy,Cancer,1970年,Vol.26, No.2,p.269-78
DE,L.E. et al,Anti-liver-kidney microsome antibody is a marker for the rat hepatocyte endoplasmic reticulum,Hepatology,1987年,Vol.7, No.3,p.468-75
ROCK,K.L. et al,Degradation of cell proteins and the generation of MHC class I-presented peptides,Annu Rev Immunol,1999年,Vol.17,p.739-79
DE,L.E. et al,Determination of the membrane topology of the phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4 using site-specific antibodies,J Cell Biol,1987年,Vol.104, No.2,p.209-19
HUGHES,L.E. et al,A study in clinical cancer immunotherapy,Cancer,1970年,Vol.26, No.2,p.269-78
DE,L.E. et al,Anti-liver-kidney microsome antibody is a marker for the rat hepatocyte endoplasmic reticulum,Hepatology,1987年,Vol.7, No.3,p.468-75
ROCK,K.L. et al,Degradation of cell proteins and the generation of MHC class I-presented peptides,Annu Rev Immunol,1999年,Vol.17,p.739-79
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi