Title:
3-セフェム誘導体結晶の製造方法
Document Type and Number:
Japanese Patent JP4953501
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a new method for producing a crystal by which a high- purity 3-cephem derivative in a crystal state is obtained from an amorphous powder or an oil of the 3-cephem derivative having extremely important stability thereof. SOLUTION: This method for producing the 3-cephem derivative crystal is characterized by carrying out crystallization of the 3-cephem derivative in the form of the amorphous powder or the oil by using a good solvent and a poor solvent comprising carbon dioxide in a supercritical or a subcritical state and thereby providing the 3-cephem derivative in the crystal state.
Inventors:
Takashi Moriyoshi
Yasuhiro Uozaki
Suzuki Daisuke
Seo fragrance
Yasuhiro Uozaki
Suzuki Daisuke
Seo fragrance
Application Number:
JP2000290561A
Publication Date:
June 13, 2012
Filing Date:
September 25, 2000
Export Citation:
Assignee:
Otsuka Chemical Co., Ltd.
International Classes:
C07D501/12; C07D501/20; C07D501/24; C07D501/59
Domestic Patent References:
| JP4500925A | ||||
| JP3258783A | ||||
| JP4283584A | ||||
| JP9132577A | ||||
| JP60011423A | ||||
| JP2277505A | ||||
| JP8169890A |
Foreign References:
| WO1999010352A1 |
Attorney, Agent or Firm:
Iwao Tamura