Title:
生体分子検出素子、生体分子検出素子の製造方法及び生体分子検出方法
Document Type and Number:
Japanese Patent JP5001019
Kind Code:
B2
Abstract:
The present invention aims to improve detecting accuracy and reproducibility of a biomolecule sensor. The biomolecule sensor of the present invention includes single probe molecules orderly aligned and fixed on grid points on the surface of a substrate. Accordingly, in the biomolecule sensor of the present invention: probe molecules for detecting a biomolecule are orderly aligned and separately fixed; blocking for preventing non-specific adsorption is applied to a region other than the region of the probe molecules for detecting a biomolecule; and fluorescence enhancement is achieved by metal microparticles.
More Like This:
Inventors:
Miwako Nakahara
Takashi Inoue
Ogi Osamu
Takashi Inoue
Ogi Osamu
Application Number:
JP2007024082A
Publication Date:
August 15, 2012
Filing Date:
February 02, 2007
Export Citation:
Assignee:
Hitachi High-Technologies Corporation
International Classes:
C12Q1/68; G01N21/78; G01N33/53; G01N33/543; C12N15/09
Domestic Patent References:
| JP2004515208A | ||||
| JP2004184143A | ||||
| JP2002204693A |
Foreign References:
| WO2001068834A1 | ||||
| WO2002063310A1 | ||||
| WO2006098446A1 |
Other References:
Nano Letters,2004年,Vol.4, No.8,pp.1521-1524
Attorney, Agent or Firm:
Yusuke Hiraki