Title:
ポリヒドロキシアルカノエートポリマーの医療デバイスおよび医療適用
Document Type and Number:
Japanese Patent JP5031144
Kind Code:
B2
Abstract:
Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating systems, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats. The polyhydroxyalkanoates can contain additives, be formed of mixtures of monomers or include pendant groups or modifications in their backbones, or can be chemically modified, all to alter the degradation rates. The polyhydroxyalkanoate compositions also provide favorable mechanical properties, biocompatibility, and degradation times within desirable time frames under physiological conditions.
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Inventors:
Williams, Simon F.
Martin, David P.
Sclery, frank
Martin, David P.
Sclery, frank
Application Number:
JP2000606279A
Publication Date:
September 19, 2012
Filing Date:
March 24, 2000
Export Citation:
Assignee:
Metabolics, Incorporated
International Classes:
A61B17/58; A61L27/00; A61B17/68; A61F2/82; A61F2/84; A61K45/00; A61L15/64; A61L17/00; A61L17/12; A61L27/18; A61L27/58; A61L31/06; A61L31/14; C08G63/06; C08K5/00; C12P7/62
Domestic Patent References:
| JP3187386A | ||||
| JP5131023A | ||||
| JP7275344A | ||||
| JP11269359A |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura