Title:
ピラゾロピリジン誘導体
Document Type and Number:
Japanese Patent JP5092402
Kind Code:
B2
Abstract:
The invention relates to compound of the formula (I) or its salt, in which R1, R2, R3 and R4 are as defined in the description, their use of as medicament, the process for their preparation and use for the treatment of PDE-IV or TNF-alpha mediated diseases.
Inventors:
Yoshito Abe
Kazuhiko radish
Kentaro Sato
Makoto Inoue
Mitsuaki Okumura
Kazuhiko radish
Kentaro Sato
Makoto Inoue
Mitsuaki Okumura
Application Number:
JP2006553787A
Publication Date:
December 05, 2012
Filing Date:
July 01, 2005
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C07D471/04; A61K31/437; A61K31/5377; A61P43/00
Domestic Patent References:
| JP2002524512A | ||||
| JP2002020386A | ||||
| JP1272584A | ||||
| JP6329540A |
Foreign References:
| WO2004024728A1 | ||||
| WO2002085906A1 |
Other References:
DIAZ-ORTIZ,A. et al,Synthesis of pyrazolo[3,4-b]pyridines by cycloaddition reactions under microwave irradiation,Tetrahedron,2000年,Vol.56, No.11,p.1569-77
ADACHI,I. et al,Studies on dihydropyridines. II. Synthesis of 4,7-dihydropyrazolo[3,4-b]pyridines with vasodilating and antihypertensive activities,Chemical & Pharmaceutical Bulletin,1987年,Vol.35, No.8,p.3235-52
ADACHI,I. et al,Studies on dihydropyridines. II. Synthesis of 4,7-dihydropyrazolo[3,4-b]pyridines with vasodilating and antihypertensive activities,Chemical & Pharmaceutical Bulletin,1987年,Vol.35, No.8,p.3235-52
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke