Title:
1,7’-ジメチル-2’-プロピル-2,5’-ビ-1H-ベンゾイミダゾールの調製及び精製方法
Document Type and Number:
Japanese Patent JP5129918
Kind Code:
B2
Abstract:
Purification of 1,7'-dimethyl-2'-propyl-2,5'-bi-1H-benzimidazole (I), obtained by reacting 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid (II) (or its salt) with N-methyl-o-phenylene diamine (III) (or its salt), comprises treating the crude product with carbon. An independent claim is also included for the use of (I) as purified above in the preparation of telmisartan.
Inventors:
Berzer Werner
Dach Rolf
Fachinger Volker
Heitzman Marx
Schmidt Hartmut
Dach Rolf
Fachinger Volker
Heitzman Marx
Schmidt Hartmut
Application Number:
JP2003559994A
Publication Date:
January 30, 2013
Filing Date:
January 15, 2003
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Gesellshaft Mitt Beschlenktel Haftung Und Company Comandito Gesellshaft
International Classes:
C07D235/20; B01D9/02; C07D235/18
Foreign References:
| US3150136 |
Other References:
J.Med.Chem.,1993年,Vol.36,No.25,p.4040-4051
化学大辞典,1993年,p.437-438「活性炭の項」
化学大辞典,1993年,p.437-438「活性炭の項」
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai